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AstraZeneca ltd gastroplus
Gastroplus, supplied by AstraZeneca ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/gastroplus/gastroplus/pm40653178-191-6-0
Average 90 stars, based on 1 article reviews
gastroplus - by Bioz Stars, 2026-09
90/100 stars

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Article Title: The influence of individual gastrointestinal physiology parameters on prediction of regional drug absorption.
Article Snippet: Physiologically based biopharmaceutics modeling (PBBM) is crucial for drug absorption prediction due to its ability to integrate drug-specific, physiological, and biopharmaceutic properties.. Recent reports highlight the need to improve prediction accuracy for regional, colonic absorption, and extended-release (ER) formulations, often using average physiological data due to rare concurrent individual measurements (e.g., luminal pH and transit time).. This investigation evaluated if in-vivo measured individual pH and transit time data could enhance absorption predictions.



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